After taking gold in the 200m individual medley S6, Ellie Simmonds will return to the pool in search of a third consecutive S6 400m freestyle gold, as wheelchair racer David Weir looks to achieve the same feat in the T54 1500m on day six.
Joining Simmonds in the pool in the same event will be Ellie Robinson, while Alice Tai, Ollie Hynd, Stephanie Millward and Stephanie Slater, are just some of the others in action. And while Weir looks to defend a title, Stephen Miller, Georgina Hermitage and Stephen Osborne also have shots at gold in the Olympic Stadium.
At the Olympic Tennis Centre there are medal chances for Andy Lapthorne and Jamie Burdekin, who are going for bronze in the men’s quad doubles, while Lucy Shuker and Jordanne Whiley also doing likewise in the women’s doubles.
Gordon Reid and Alfie Hewett face men’s single quarter-finals, as well as a doubles semi-final together. While at Riocentro, Robert Davies goes for gold in the men’s table tennis class one singles against Korea's Joo Young Dae.
Tuesday also sees the start of GB’s wheelchair fencing campaign as Dimitri Coutya goes in the men’s individual epee category B preliminary rounds, while Gemma Collis and Piers Gilliver also enter the fray.
In the boccia David Smith begins the BC1 mixed individual event, with Joshua Rowe and Nigel Murray in the BC2, while Kieran Steer and Stephen McGuire go in the BC4 event, and Natasha Baker completes Britain’s first involvement in the equestrian Team Test after strong outings for Sophie Wells, Sophie Christiansen and Anne Dunham on Monday.
The women’s wheelchair basketball team has reached the quarter-final stage where they take on China, while recurve archer David Phillips begins his men’s individual campaign in the 1/16 elimination round.
From dry land to the Marina da Gloria and Great Britain have sailors going in the one, two and three-person keelboat classes, with Helena Lucas well placed.
And at the Olympic shooting range Karen Butler and Lorraine Lambert compete in the R8 women’s 50m rifle, three-position, competition, while James Bevis, Ryan Cockbill and Tim Jeffery start their R5 mixed 10m air rifle, prone, qualification campaign.
Medal highlights for the day ahead are below (times denoted are BST) and for results and medal table, visit our interactive micro-site #EVERYROADtoRIO Live. Catch up with events from yesterday, here.
You can also keep up with key moments from the Paralympics by following @UK_Sport on Twitter.
Tuesday 13 September
Athletics
F32 club throw; Stephen Miller (14:03)
T37 400m; Georgina Hermitage (14:14)
T51 100m; Stephen Osborne (14:34)
T20 1500m; Steve Morris (14:55)
F46 javelin; Hollie Arnold (15:04)
T34 400m heats; Hannah Cockroft, Kare Adenegan (heats 15:52, final 21:40)
T54 1500m; David Weir (22:22)
Swimming
S6 400m heats; Ellie Simmonds, Ellie Robinson (final 21:41)
S10 100m free; Alice Tai (final 22:17)
S8 100m backstroke; Ollie Hynd (final 23:19)
S8 100m backstroke; Steph Slater, Steph Millward (23:26)
Wheelchair Tennis (from 16:00)
Men’s Singles quarter-finals; Gordon Reid
Women’s Singles semi-finals; Jordanne Whiley, Lucy Shuker
Women’s Doubles; Jordanne Whiley and Lucy Shuker
Men’s Doubles; Andy Lapthorne and Jamie Burdekin
Wheelchair Fencing
Men’s Individual Epee B; Dimitri Coutya (pools 13:00, quarters 15:25, semi-final and bronze medal match 18:00, gold medal match 21:17)
Men’s Individual Epee A; Piers Gilliver (pools 13:00, quarters 15:25, semi-final and bronze medal match 18:30, gold medal match 21:47)
Women’s Individual Epee A; Gemma Collis (pools 13:00, semi-final and bronze medal match 18:30, gold medal match 20:30)
Shooting
Women’s R8 50m rifle 3 Position SH1; Lorraine Lambert, Karen Butler (qualification 13:30, final 16:30)
Men’s R5 10m Prone SH2; Tim Jeffery, James Bevis, Ryan Cockbill (qualification 17:00, final 19:15)
Archery
Individual recurve; David Phillips (last 32 from 13:00, gold medal match 22:45)
Table Tennis
SM1 Rob Davies (16:45)
Equestrian
Grade II team test; Natasha Baker (14:00)
R3 mixed 10m air rifle; Matt Skelhon (qualification 13:30, final 15:45)